Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

H2ax  H2A.X variant histone   (Synonyms: gammaH2ax, H2afx, H2A.X, Hist5-2ax)
Results	Reference
1*	J:231231 Abby E, Tourpin S, Ribeiro J, Daniel K, Messiaen S, Moison D, Guerquin J, Gaillard JC, Armengaud J, Langa F, Toth A, Martini E, Livera G, Implementation of meiosis prophase I programme requires a conserved retinoid-independent stabilizer of meiotic transcripts. Nat Commun. 2016;7:10324
1	J:320348 Aditi, Downing SM, Schreiner PA, Kwak YD, Li Y, Shaw TI, Russell HR, McKinnon PJ, Genome instability independent of type I interferon signaling drives neuropathology caused by impaired ribonucleotide excision repair. Neuron. 2021 Dec 15;109(24):3962-3979.e6
1	J:289968 Bae J-H, Hong M, Jeong H-J, Kim H, Lee S-J, Ryu D, Bae G-U, Cho SC, Lee Y-S, Krauss RS, Kang J-S, Satellite Cell-Specific Ablation of Cdon Impairs Integrin Activation, FGF Signalling, and Muscle Regeneration. J Cachexia Sarcopenia Muscle. 2020;
1*	J:253477 Bailey AS, Batista PJ, Gold RS, Chen YG, de Rooij DG, Chang HY, Fuller MT, The conserved RNA helicase YTHDC2 regulates the transition from proliferation to differentiation in the germline. Elife. 2017 Oct 31;6:e26116
1	J:213136 Baker MD, Ezzati M, Aloisio GM, Tarnawa ED, Cuevas I, Nakada Y, Castrillon DH, The small GTPase Rheb is required for spermatogenesis but not oogenesis. Reproduction. 2014 May;147(5):615-25
1	J:186357 Baleriola J, Suarez T, de la Rosa EJ, DNA-PK promotes the survival of young neurons in the embryonic mouse retina. Cell Death Differ. 2010 Nov;17(11):1697-706
1*	J:146199 Barrionuevo F, Georg I, Scherthan H, Lecureuil C, Guillou F, Wegner M, Scherer G, Testis cord differentiation after the sex determination stage is independent of Sox9 but fails in the combined absence of Sox9 and Sox8. Dev Biol. 2009 Mar 15;327(2):301-12
1	J:276773 Beeler JS, Marshall CB, Gonzalez-Ericsson PI, Shaver TM, Santos Guasch GL, Lea ST, Johnson KN, Jin H, Venters BJ, Sanders ME, Pietenpol JA, p73 regulates epidermal wound healing and induced keratinocyte programming. PLoS One. 2019;14(6):e0218458
1	J:185876 Bordlein A, Scherthan H, Nelkenbrecher C, Molter T, Bosl MR, Dippold C, Birke K, Kinkley S, Staege H, Will H, Winterpacht A, SPOC1 (PHF13) is required for spermatogonial stem cell differentiation and sustained spermatogenesis. J Cell Sci. 2011 Sep 15;124(Pt 18):3137-48
1	J:125911 Cang Y, Zhang J, Nicholas SA, Kim AL, Zhou P, Goff SP, DDB1 is essential for genomic stability in developing epidermis. Proc Natl Acad Sci U S A. 2007 Feb 20;104(8):2733-7
1	J:226418 Caserta E, Egriboz O, Wang H, Martin C, Koivisto C, Pecot T, Kladney RD, Shen C, Shim KS, Pham T, Karikomi MK, Mauntel MJ, Majumder S, Cuitino MC, Tang X, Srivastava A, Yu L, Wallace J, Mo X, Park M, Fernandez SA, Pilarski R, La Perle KM, Rosol TJ, Coppola V, Castrillon DH, Timmers C, Cohn DE, O'Malley DM, Backes F, Suarez AA, Goodfellow P, Chamberlin HM, Macrae ER, Shapiro CL, Ostrowski MC, Leone G, Noncatalytic PTEN missense mutation predisposes to organ-selective cancer development in vivo. Genes Dev. 2015 Aug 15;29(16):1707-20
1	J:212971 Cavalheiro GR, Matos-Rodrigues GE, Gomes AL, Rodrigues PM, Martins RA, c-myc regulates cell proliferation during lens development. PLoS One. 2014;9(2):e87182
1	J:249114 Cavalheiro GR, Matos-Rodrigues GE, Zhao Y, Gomes AL, Anand D, Predes D, de Lima S, Abreu JG, Zheng D, Lachke SA, Cvekl A, Martins RAP, N-myc regulates growth and fiber cell differentiation in lens development. Dev Biol. 2017 Sep 1;429(1):105-117
1	J:333943 Cen C, Chen J, Lin L, Chen M, Dong F, Shen Z, Cui X, Hou X, Gao F, Fancb deficiency causes premature ovarian insufficiency in mice. Biol Reprod. 2022 Sep 12;107(3):790-799
1	J:310334 Chen B, Zhu G, Yan A, He J, Liu Y, Li L, Yang X, Dong C, Kee K, IGSF11 is required for pericentric heterochromatin dissociation during meiotic diplotene. PLoS Genet. 2021 Sep;17(9):e1009778
1	J:325357 Chomiak AA, Guo Y, Kopsidas CA, McDaniel DP, Lowe CC, Pan H, Zhou X, Zhou Q, Doughty ML, Feng Y, Nde1 is required for heterochromatin compaction and stability in neocortical neurons. iScience. 2022 Jun 17;25(6):104354
1	J:307645 Dai XX, Jiang Y, Gu JH, Jiang ZY, Wu YW, Yu C, Yin H, Zhang J, Shi QH, Shen L, Sha QQ, Fan HY, The CNOT4 Subunit of the CCR4-NOT Complex is Involved in mRNA Degradation, Efficient DNA Damage Repair, and XY Chromosome Crossover during Male Germ Cell Meiosis. Adv Sci (Weinh). 2021 May;8(10):2003636
1	J:342617 Dali O, D'Cruz S, Legoff L, Diba Lahmidi M, Heitz C, Merret PE, Kernanec PY, Pakdel F, Smagulova F, Transgenerational epigenetic effects imposed by neonicotinoid thiacloprid exposure. Life Sci Alliance. 2024 Feb;7(2)
1	J:326549 Dang H, Martin-Villalba A, Schiebel E, Centrosome linker protein C-Nap1 maintains stem cells in mouse testes. EMBO Rep. 2022 Jul 5;23(7):e53805
1	J:173089 Daniel K, Lange J, Hached K, Fu J, Anastassiadis K, Roig I, Cooke HJ, Stewart AF, Wassmann K, Jasin M, Keeney S, Toth A, Meiotic homologue alignment and its quality surveillance are controlled by mouse HORMAD1. Nat Cell Biol. 2011 May;13(5):599-610
1	J:297431 Dewhurst MR, Ow JR, Zafer G, van Hul NKM, Wollmann H, Bisteau X, Brough D, Choi H, Kaldis P, Loss of hepatocyte cell division leads to liver inflammation and fibrosis. PLoS Genet. 2020 Nov;16(11):e1009084
1	J:325537 Dong MZ, Ouyang YC, Gao SC, Ma XS, Hou Y, Schatten H, Wang ZB, Sun QY, PPP4C facilitates homologous recombination DNA repair by dephosphorylating PLK1 during early embryo development. Development. 2022 May 15;149(10):dev200351
1	J:269212 Dumitrache LC, Shimada M, Downing SM, Kwak YD, Li Y, Illuzzi JL, Russell HR, Wilson DM 3rd, McKinnon PJ, Apurinic endonuclease-1 preserves neural genome integrity to maintain homeostasis and thermoregulation and prevent brain tumors. Proc Natl Acad Sci U S A. 2018 Dec 26;115(52):E12285-E12294
1	J:206141 Eguren M, Porlan E, Manchado E, Garcia-Higuera I, Canamero M, Farinas I, Malumbres M, The APC/C cofactor Cdh1 prevents replicative stress and p53-dependent cell death in neural progenitors. Nat Commun. 2013;4:2880
1	J:224084 Elliott EN, Sheaffer KL, Schug J, Stappenbeck TS, Kaestner KH, Dnmt1 is essential to maintain progenitors in the perinatal intestinal epithelium. Development. 2015 Jun 15;142(12):2163-72
1	J:196310 Ene AC, Park S, Edelmann W, Taketo T, Caspase 9 is constitutively activated in mouse oocytes and plays a key role in oocyte elimination during meiotic prophase progression. Dev Biol. 2013 May 1;377(1):213-23
1	J:239152 Enriquez-Rios V, Dumitrache LC, Downing SM, Li Y, Brown EJ, Russell HR, McKinnon PJ, DNA-PKcs, ATM, and ATR Interplay Maintains Genome Integrity during Neurogenesis. J Neurosci. 2017 Jan 25;37(4):893-905
1	J:303558 Felipe-Medina N, Caburet S, Sanchez-Saez F, Condezo YB, de Rooij DG, Gomez-H L, Garcia-Valiente R, Todeschini AL, Duque P, Sanchez-Martin MA, Shalev SA, Llano E, Veitia RA, Pendas AM, A missense in HSF2BP causing primary ovarian insufficiency affects meiotic recombination by its novel interactor C19ORF57/BRME1. Elife. 2020 Aug 26;9:e56996
1	J:326362 Feng S, Li J, Wen H, Liu K, Gui Y, Wen Y, Wang X, Yuan S, hnRNPH1 recruits PTBP2 and SRSF3 to modulate alternative splicing in germ cells. Nat Commun. 2022 Jun 23;13(1):3588
1	J:275030 Ferder IC, Fung L, Ohguchi Y, Zhang X, Lassen KG, Capen D, Brown D, Xavier RJ, Wang N, Meiotic gatekeeper STRA8 suppresses autophagy by repressing Nr1d1 expression during spermatogenesis in mice. PLoS Genet. 2019 May;15(5):e1008084
1	J:265597 Gao X, Ma W, Nie J, Zhang C, Zhang J, Yao G, Han J, Xu J, Hu B, Du Y, Shi Q, Yang Z, Huang X, Zhang Y, A G-quadruplex DNA structure resolvase, RHAU, is essential for spermatogonia differentiation. Cell Death Dis. 2015 Jan 22;6:e1610
1	J:246072 Golson ML, Dunn JC, Maulis MF, Dadi PK, Osipovich AB, Magnuson MA, Jacobson DA, Gannon M, Activation of FoxM1 Revitalizes the Replicative Potential of Aged beta-Cells in Male Mice and Enhances Insulin Secretion. Diabetes. 2015 Nov;64(11):3829-38
1	J:239805 Grigaravicius P, Kaminska E, Hubner CA, McKinnon PJ, von Deimling A, Frappart PO, Rint1 inactivation triggers genomic instability, ER stress and autophagy inhibition in the brain. Cell Death Differ. 2016 Mar;23(3):454-68
1	J:325094 Guan Y, Lin H, Leu NA, Ruthel G, Fuchs SY, Busino L, Luo M, Wang PJ, SCF ubiquitin E3 ligase regulates DNA double-strand breaks in early meiotic recombination. Nucleic Acids Res. 2022 May 20;50(9):5129-5144
1	J:311067 Gygli PE, Chang JC, Gokozan HN, Catacutan FP, Schmidt TA, Kaya B, Goksel M, Baig FS, Chen S, Griveau A, Michowski W, Wong M, Palanichamy K, Sicinski P, Nelson RJ, Czeisler C, Otero JJ, Cyclin A2 promotes DNA repair in the brain during both development and aging. Aging (Albany NY). 2016 Jul;8(7):1540-70
1	J:225041 Hasegawa K, Sin HS, Maezawa S, Broering TJ, Kartashov AV, Alavattam KG, Ichijima Y, Zhang F, Bacon WC, Greis KD, Andreassen PR, Barski A, Namekawa SH, SCML2 establishes the male germline epigenome through regulation of histone H2A ubiquitination. Dev Cell. 2015 Mar 9;32(5):574-88
1	J:293102 Heinrich A, Potter SJ, Guo L, Ratner N, DeFalco T, Distinct Roles for Rac1 in Sertoli Cell Function during Testicular Development and Spermatogenesis. Cell Rep. 2020 Apr 14;31(2):107513
1	J:208416 Holt JE, Pye V, Boon E, Stewart JL, Garcia-Higuera I, Moreno S, Rodriguez R, Jones KT, McLaughlin EA, The APC/C activator FZR1 is essential for meiotic prophase I in mice. Development. 2014 Mar;141(6):1354-65
1	J:307864 Horisawa-Takada Y, Kodera C, Takemoto K, Sakashita A, Horisawa K, Maeda R, Shimada R, Usuki S, Fujimura S, Tani N, Matsuura K, Akiyama T, Suzuki A, Niwa H, Tachibana M, Ohba T, Katabuchi H, Namekawa SH, Araki K, Ishiguro KI, Meiosis-specific ZFP541 repressor complex promotes developmental progression of meiotic prophase towards completion during mouse spermatogenesis. Nat Commun. 2021 Jun 1;12(1):3184
1	J:335565 Huang T, Wu X, Wang S, Bao Z, Wan Y, Wang Z, Li M, Yu X, Lv Y, Liu Z, Chen X, Chan WY, Gao F, Lu G, Chen ZJ, Liu H, SPIDR is required for homologous recombination during mammalian meiosis. Nucleic Acids Res. 2023 May 8;51(8):3855-3868
1	J:203322 Hussain S, Tuorto F, Menon S, Blanco S, Cox C, Flores JV, Watt S, Kudo NR, Lyko F, Frye M, The mouse cytosine-5 RNA methyltransferase NSun2 is a component of the chromatoid body and required for testis differentiation. Mol Cell Biol. 2013 Apr;33(8):1561-70
1	J:316710 Inagaki A, Roset R, Petrini JH, Functions of the MRE11 complex in the development and maintenance of oocytes. Chromosoma. 2016 Mar;125(1):151-62
1*	J:290712 Ishiguro KI, Matsuura K, Tani N, Takeda N, Usuki S, Yamane M, Sugimoto M, Fujimura S, Hosokawa M, Chuma S, Ko MSH, Araki K, Niwa H, MEIOSIN Directs the Switch from Mitosis to Meiosis in Mammalian Germ Cells. Dev Cell. 2020 Feb 24;52(4):429-445.e10
1	J:289708 Jiang X, Yin S, Fan S, Bao J, Jiao Y, Ali A, Iqbal F, Xu J, Zhang Y, Shi Q, Npat-dependent programmed Sertoli cell proliferation is indispensable for testis cord development and germ cell mitotic arrest. FASEB J. 2019 Aug;33(8):9075-9086
1*	J:286601 Jiang Y, Zhang HY, Lin Z, Zhu YZ, Yu C, Sha QQ, Tong MH, Shen L, Fan HY, CXXC finger protein 1-mediated histone H3 lysine-4 trimethylation is essential for proper meiotic crossover formation in mice. Development. 2020 Mar 17;147(6):dev183764
1	J:224588 Kato Y, Alavattam KG, Sin HS, Meetei AR, Pang Q, Andreassen PR, Namekawa SH, FANCB is essential in the male germline and regulates H3K9 methylation on the sex chromosomes during meiosis. Hum Mol Genet. 2015 Sep 15;24(18):5234-49
1	J:339369 Kaur G, Helmer RA, Martinez-Marin D, Sennoune SR, Washburn RL, Martinez-Zaguilan R, Dufour JM, Chilton BS, Helicase-like transcription factor (Hltf)-deletion activates Hmgb1-Rage axis and granzyme A-mediated killing of pancreatic beta cells resulting in neonatal lethality. PLoS One. 2023;18(8):e0286109
1	J:329968 Kazi S, Castaneda JM, Savolainen A, Xu Y, Liu N, Qiao H, Ramirez-Solis R, Nozawa K, Yu Z, Matzuk MM, Prunskaite-Hyyrylainen R, MRNIP interacts with sex body chromatin to support meiotic progression, spermatogenesis, and male fertility in mice. FASEB J. 2022 Sep;36(9):e22479
1	J:159668 Kim GJ, Georg I, Scherthan H, Merkenschlager M, Guillou F, Scherer G, Barrionuevo F, Dicer is required for Sertoli cell function and survival. Int J Dev Biol. 2010;54(5):867-75
1	J:309383 Kim J, Choi I, Lee Y, Involvement of Atm and Trp53 in neural cell loss due to Terf2 inactivation during mouse brain development. Histochem Cell Biol. 2017 Nov;148(5):489-501
1	J:286844 Kim J, Kim K, Mo JS, Lee Y, Atm deficiency in the DNA polymerase beta null cerebellum results in cerebellar ataxia and Itpr1 reduction associated with alteration of cytosine methylation. Nucleic Acids Res. 2020 Apr 17;48(7):3678-3691
1	J:213984 Kogo H, Tsutsumi M, Ohye T, Inagaki H, Abe T, Kurahashi H, HORMAD1-dependent checkpoint/surveillance mechanism eliminates asynaptic oocytes. Genes Cells. 2012 Jun;17(6):439-54
1*	J:223515 Kunze S, Dalke C, Fuchs H, Klaften M, Rossler U, Hornhardt S, Gomolka M, Puk O, Sabrautzki S, Kulka U, Hrabe de Angelis M, Graw J, New mutation in the mouse xpd/ercc2 gene leads to recessive cataracts. PLoS One. 2015;10(5):e0125304
1	J:87735 Kuramochi-Miyagawa S, Kimura T, Ijiri TW, Isobe T, Asada N, Fujita Y, Ikawa M, Iwai N, Okabe M, Deng W, Lin H, Matsuda Y, Nakano T, Mili, a mammalian member of piwi family gene, is essential for spermatogenesis. Development. 2004 Feb;131(4):839-49
1	J:220996 La Sala G, Marazziti D, Di Pietro C, Golini E, Matteoni R, Tocchini-Valentini GP, Modulation of Dhh signaling and altered Sertoli cell function in mice lacking the GPR37-prosaposin receptor. FASEB J. 2015 May;29(5):2059-69
1	J:194924 Lavery R, Chassot AA, Pauper E, Gregoire EP, Klopfenstein M, de Rooij DG, Mark M, Schedl A, Ghyselinck NB, Chaboissier MC, Testicular differentiation occurs in absence of R-spondin1 and Sox9 in mouse sex reversals. PLoS Genet. 2012;8(12):e1003170
1	J:211631 Lee Y, Brown EJ, Chang S, McKinnon PJ, Pot1a prevents telomere dysfunction and ATM-dependent neuronal loss. J Neurosci. 2014 Jun 4;34(23):7836-44
1	J:191367 Lee Y, Katyal S, Downing SM, Zhao J, Russell HR, McKinnon PJ, Neurogenesis requires TopBP1 to prevent catastrophic replicative DNA damage in early progenitors. Nat Neurosci. 2012 Jun;15(6):819-26
1	J:152528 Lee Y, Katyal S, Li Y, El-Khamisy SF, Russell HR, Caldecott KW, McKinnon PJ, The genesis of cerebellar interneurons and the prevention of neural DNA damage require XRCC1. Nat Neurosci. 2009 Aug;12(8):973-80
1	J:181920 Lee Y, Shull ER, Frappart PO, Katyal S, Enriquez-Rios V, Zhao J, Russell HR, Brown EJ, McKinnon PJ, ATR maintains select progenitors during nervous system development. EMBO J. 2012 Mar 7;31(5):1177-89
1	J:191599 Li J, Jiang TX, Hughes MW, Wu P, Widelitz RB, Fan G, Chuong CM, Progressive alopecia reveals decreasing stem cell activation probability during aging of mice with epidermal deletion of DNA methyltransferase 1. J Invest Dermatol. 2012 Dec;132(12):2681-90
1	J:306603 Li J, Shang Y, Wang L, Zhao B, Sun C, Li J, Liu S, Li C, Tang M, Meng FL, Zheng P, Genome integrity and neurogenesis of postnatal hippocampal neural stem/progenitor cells require a unique regulator Filia. Sci Adv. 2020 Oct;6(44)
1	J:306873 Li L, Jin J, Yang XJ, Histone Deacetylase 3 Governs Perinatal Cerebral Development via Neural Stem and Progenitor Cells. iScience. 2019 Oct 25;20:148-167
1*	J:278517 Li M, Huang T, Li MJ, Zhang CX, Yu XC, Yin YY, Liu C, Wang X, Feng HW, Zhang T, Liu MF, Han CS, Lu G, Li W, Ma JL, Chen ZJ, Liu HB, Liu K, The histone modification reader ZCWPW1 is required for meiosis prophase I in male but not in female mice. Sci Adv. 2019;5(8):eaax1101
1*	J:303646 Li M, Zheng J, Li G, Lin Z, Li D, Liu D, Feng H, Cao D, Ng EHY, Li RHW, Han C, Yeung WSB, Chow LT, Wang H, Liu K, The male germline-specific protein MAPS is indispensable for pachynema progression and fertility. Proc Natl Acad Sci U S A. 2021 Feb 23;118(8):e2025421118
1	J:207483 Li Y, Hao H, Tzatzalos E, Lin RK, Doh S, Liu LF, Lyu YL, Cai L, Topoisomerase IIbeta is required for proper retinal development and survival of postmitotic cells. Biol Open. 2014;3(2):172-84
1*	J:285969 Liu H, Huang T, Li M, Li M, Zhang C, Jiang J, Yu X, Yin Y, Zhang F, Lu G, Luo MC, Zhang LR, Li J, Liu K, Chen ZJ, SCRE serves as a unique synaptonemal complex fastener and is essential for progression of meiosis prophase I in mice. Nucleic Acids Res. 2019 Jun 20;47(11):5670-5683
1	J:244859 Liu W, Wang F, Xu Q, Shi J, Zhang X, Lu X, Zhao ZA, Gao Z, Ma H, Duan E, Gao F, Gao S, Yi Z, Li L, BCAS2 is involved in alternative mRNA splicing in spermatogonia and the transition to meiosis. Nat Commun. 2017 Jan 27;8:14182
1	J:294981 Liu X, Castle V, Taketo T, Interplay between Caspase 9 and X-linked Inhibitor of Apoptosis Protein (XIAP) in the oocyte elimination during fetal mouse development. Cell Death Dis. 2019 Oct 17;10(11):790
1	J:274694 Lodge EJ, Santambrogio A, Russell JP, Xekouki P, Jacques TS, Johnson RL, Thavaraj S, Bornstein SR, Andoniadou CL, Homeostatic and tumourigenic activity of SOX2+ pituitary stem cells is controlled by the LATS/YAP/TAZ cascade. Elife. 2019 Mar 26;8:e43996
1	J:182697 Lopez-Contreras AJ, Gutierrez-Martinez P, Specks J, Rodrigo-Perez S, Fernandez-Capetillo O, An extra allele of Chk1 limits oncogene-induced replicative stress and promotes transformation. J Exp Med. 2012 Mar 12;209(3):455-61
1	J:224165 Lovasco LA, Gustafson EA, Seymour KA, de Rooij DG, Freiman RN, TAF4b is required for mouse spermatogonial stem cell development. Stem Cells. 2015 Apr;33(4):1267-76
1	J:222892 Luo M, Zhou J, Leu NA, Abreu CM, Wang J, Anguera MC, de Rooij DG, Jasin M, Wang PJ, Polycomb protein SCML2 associates with USP7 and counteracts histone H2A ubiquitination in the XY chromatin during male meiosis. PLoS Genet. 2015 Jan;11(1):e1004954
1	J:228047 Luo Y, Hartford SA, Zeng R, Southard TL, Shima N, Schimenti JC, Hypersensitivity of primordial germ cells to compromised replication-associated DNA repair involves ATM-p53-p21 signaling. PLoS Genet. 2014 Jul;10(7):e1004471
1*	J:285730 Major AT, Hogarth CA, Young JC, Kurihara Y, Jans DA, Loveland KL, Dynamic paraspeckle component localisation during spermatogenesis. Reproduction. 2019 Sep;158(3):267-280
1	J:185038 Martinez P, Flores JM, Blasco MA, 53BP1 deficiency combined with telomere dysfunction activates ATR-dependent DNA damage response. J Cell Biol. 2012 Apr 16;197(2):283-300
1	J:299031 Matos-Rodrigues GE, Grigaravicius P, Lopez BS, Hofmann TG, Frappart PO, Martins RAP, ATRIP protects progenitor cells against DNA damage in vivo. Cell Death Dis. 2020 Oct 28;11(10):923
1*	J:297493 Matos-Rodrigues GE, Tan PB, Rocha-Martins M, Charlier CF, Gomes AL, Cabral-Miranda F, Grigaravicius P, Hofmann TG, Frappart PO, Martins RAP, Progenitor death drives retinal dysplasia and neuronal degeneration in a mouse model of ATRIP-Seckel syndrome. Dis Model Mech. 2020 Oct 30;13(10):dmm045807
1	J:309380 Mei L, Qv M, Bao H, He Q, Xu Y, Zhang Q, Shi W, Ren Q, Yan Z, Xu C, Tang C, Hussain M, Zeng LH, Wu X, SUMOylation activates large tumour suppressor 1 to maintain the tissue homeostasis during Hippo signalling. Oncogene. 2021 Sep;40(35):5357-5366
1*	J:241010 Mu W, Starmer J, Shibata Y, Yee D, Magnuson T, EZH1 in germ cells safeguards the function of PRC2 during spermatogenesis. Dev Biol. 2017 Apr 15;424(2):198-207
1	J:151542 Murga M, Bunting S, Montana MF, Soria R, Mulero F, Canamero M, Lee Y, McKinnon PJ, Nussenzweig A, Fernandez-Capetillo O, A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging. Nat Genet. 2009 Aug;41(8):891-8
1	J:214297 Myers M, Morgan FH, Liew SH, Zerafa N, Gamage TU, Sarraj M, Cook M, Kapic I, Sutherland A, Scott CL, Strasser A, Findlay JK, Kerr JB, Hutt KJ, PUMA regulates germ cell loss and primordial follicle endowment in mice. Reproduction. 2014 Aug;148(2):211-9
1	J:285778 Nagaoka SI, Nakaki F, Miyauchi H, Nosaka Y, Ohta H, Yabuta Y, Kurimoto K, Hayashi K, Nakamura T, Yamamoto T, Saitou M, ZGLP1 is a determinant for the oogenic fate in mice. Science. 2020 Mar 6;367(6482)
1	J:301847 Ni L, Xie H, Tan L, Multiple roles of FOXJ3 in spermatogenesis: A lesson from Foxj3 conditional knockout mouse models. Mol Reprod Dev. 2016 Dec;83(12):1060-1069
1	J:219210 Nikolaou KC, Moulos P, Chalepakis G, Hatzis P, Oda H, Reinberg D, Talianidis I, Spontaneous development of hepatocellular carcinoma with cancer stem cell properties in PR-SET7-deficient livers. EMBO J. 2015 Feb 12;34(4):430-47
1	J:99790 Ottolenghi C, Omari S, Garcia-Ortiz JE, Uda M, Crisponi L, Forabosco A, Pilia G, Schlessinger D, Foxl2 is required for commitment to ovary differentiation. Hum Mol Genet. 2005 Jul 15;14(14):2053-62
1	J:222045 Padua MB, Jiang T, Morse DA, Fox SC, Hatch HM, Tevosian SG, Combined loss of the GATA4 and GATA6 transcription factors in male mice disrupts testicular development and confers adrenal-like function in the testes. Endocrinology. 2015 May;156(5):1873-86
1	J:327300 Pakarinen E, Lindholm P, Saarma M, Lindahl M, CDNF and MANF regulate ER stress in a tissue-specific manner. Cell Mol Life Sci. 2022 Feb 7;79(2):124
1	J:202012 Pandey RR, Tokuzawa Y, Yang Z, Hayashi E, Ichisaka T, Kajita S, Asano Y, Kunieda T, Sachidanandam R, Chuma S, Yamanaka S, Pillai RS, Tudor domain containing 12 (TDRD12) is essential for secondary PIWI interacting RNA biogenesis in mice. Proc Natl Acad Sci U S A. 2013 Oct 8;110(41):16492-7
1	J:335234 Parveen N, Wang JK, Bhattacharya S, Cuala J, Singh Rajkumar M, Butler AE, Wu X, Shih HP, Georgia SK, Dhawan S, DNA methylation Dependent Restriction of Tyrosine Hydroxylase Contributes to Pancreatic beta-cell Heterogeneity. Diabetes. 2023 Jan 6;72(5):575-89
1	J:223048 Pirouz M, Pilarski S, Kessel M, A critical function of Mad2l2 in primordial germ cell development of mice. PLoS Genet. 2013 Aug;9(8):e1003712
1*	J:180513 Posey KL, Coustry F, Veerisetty AC, Liu P, Alcorn JL, Hecht JT, Chop (Ddit3) Is Essential for D469del-COMP Retention and Cell Death in Chondrocytes in an Inducible Transgenic Mouse Model of Pseudoachondroplasia. Am J Pathol. 2012 Feb;180(2):727-37
1	J:324159 Qin J, Huang T, Wang J, Xu L, Dang Q, Xu X, Liu H, Liu Z, Shao C, Zhang X, RAD51 is essential for spermatogenesis and male fertility in mice. Cell Death Discov. 2022 Mar 15;8(1):118
1	J:259872 Quereda V, Porlan E, Canamero M, Dubus P, Malumbres M, An essential role for Ink4 and Cip/Kip cell-cycle inhibitors in preventing replicative stress. Cell Death Differ. 2016 Mar;23(3):430-41
1*	J:138760 Reynard LN, Turner JM, Cocquet J, Mahadevaiah SK, Toure A, Hoog C, Burgoyne PS, Expression analysis of the mouse multi-copy X-linked gene Xlr-related, meiosis-regulated (Xmr), reveals that Xmr encodes a spermatid-expressed cytoplasmic protein, SLX/XMR. Biol Reprod. 2007 Aug;77(2):329-35
1*	J:229524 Robert T, Nore A, Brun C, Maffre C, Crimi B, Bourbon HM, de Massy B, The TopoVIB-Like protein family is required for meiotic DNA double-strand break formation. Science. 2016 Feb 26;351(6276):943-9
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